Nasal Drug Delivery

MedPharm has extensive expertise in nasal drug delivery formulation development in order to produce systemic or local drug delivery for a variety of diseases.

All formulations developed by MedPharm are being targeted towards maximum thermodynamic activity (i.e. saturated solubility) as this generally leads to a maximum driving force and greatest flux of the drug. Thus, the formulations to be developed should be:

  • Stable,
  • Non-irritant,
  • Non-toxic,
  • Non-odorous,

 

and achieve optimum delivery as solutions, suspensions or dry powders when applied in the form of the following nasal delivery systems:

  • Drops,
  • Sprays,
  • Gels,
  • Powders.

 

The Cell Culture Unit has the expertise to study the release and the absorption of the drug across the mucous membrane. (See in vitro studies)