MedSpray™ : Patch in a Can®

Product description

MedSprayT is a patented self-assembling Patch in a can ® technology which optimizes topical and transdermal drug delivery by overcoming the barrier properties of the stratum corneum .

MedSprayT provides a sprayable pharmaceutical formulation capable of forming a microthin film on topical administration that simply washes off after use, if required. The properties of the film can be manipulated to achieve the required drug delivery and film properties in terms of tackiness, viscosity and water resistance.

Background

The administration of therapeutic compounds either locally to the skin, or into the systemic circulation after passage through the skin, offers numerous potential advantages over oral or parenteral drug delivery. These include the avoidance of hepatic first-pass metabolism, improved patient compliance and ease of access to the absorbing membrane, i.e . the skin.

In order for therapeutic quantities of drug to penetrate the skin, the barrier properties of the stratum corneum must be overcome. Methods of overcoming this highly effective barrier may be divided into chemical, such as the use of occlusion, penetration enhancers and supersaturated systems, and physical, such as iontophoresis, skin electroporation, ultrasound and microneedle methods. Many of the techniques currently under investigation are based on a combination of these approaches and as such can be costly, unsuitable for certain drugs or cause skin damage.

MedSprayT is a simple, easy to use and cost effective drug delivery technology that contains a patented combination of commonly used pharmaceutical excipients.

Benefits of MedSpray™

• Self-assembling, elegant formulation
• Highly efficient local or transdermal delivery
• Low manufacturing cost
• Easy to use
• Patient friendly
• Non-invasive
• Suitable for hairy skin

Current Patent Status

PCT application filed September 2006. PCT/GB2006/00340

To download the MedSpray leaflet click on MedSpray™