Analytical Services

The team of pharmaceutical and analytical experts at MedPharm is experienced in a large variety of chemical and physical characterisation methods and can provide a high-quality analytical service tailored to the specific requirements of the respective project. MedPharm can undertake:

  • Solubility studies, logP and pKa determination
  • Investigation of crystalline states and polymorphism
  • Method development and validation to ICH requirements
  • Isolation and identification of impurities, degradation products and metabolites
  • Stress modelling for drug substances and drug products
  • Dissolution testing to BP and USP requirements
  • IVRT
  • Tissue permeation and penetration testing
  • Particle sizing
  • Stability testing to ICH guidelines
  • Microscopical and rheological characterisation

MedPharm utilises a broad range of analytical techniques that allow quantification of the vast majority of APIs. These include:

  • HPLC with UV (dual wavelength), PDA, MS, – fluorescence detectors
  • UHPLC with UV (dual wavelength) detectors
  • LC-MS/MS
  • GC-MS
  • ICP-MS
  • Size exclusion and ion pair chromatography
  • Gel electrophoresis
  • Immunoassays
  • Modulated Differential Scanning Calorimetry
  • (MtDSC)
  • Thermogravimetric Analysis (TGA)
  • Spectroscopic techniques;  Raman and Infrared Scanning laser microscopy

MedPharm LCMS equipment-321